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The authors declare that data supporting the findings of this study are available within the article and its supplementary information files or from the corresponding author upon reasonable request. Data for microarray analyses have been deposited in the Gene Expression Omnibus (GEO) database under accession codes GSE128868 and GSE131789. All proteomic datasets are available to download from the data repository of University of Maryland metallotherapeutics research center, Baltimore [ ] and the mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD013854. All raw images of western blot for Figs. 1g, 3a, 3b, 4b, 4d, 4h, 5a and 5b are provided in the Source data file. 59ce067264

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